O'Brien Lab

News

DATE NEWS ITEM
June 6th, 2017 Congratulations to members of the Bukau Lab and collaborators Ed O’Brien and Nabeel Ahmed on the acceptance of their manuscript “Profiling of Ssb interactions with nascent proteins reveals principles of Hsp70 assisted co-translational folding” at Cell.
May 20th, 2017 Congratulations to O’Brien Lab members Sarah Leininger and Dan Nissley, who both received awards for excellence in poster presentation at CBSB 2017.
May 19th, 2017 Ed O’Brien gave an invited talk titled “Non-equilibrium physics in nascent protein structure and function” at CBSB 2017. Click here for more information.
March 21st, 2017 Congratulations to Ed O’Brien for receiving the 2016 Priestley Prize for excellence in undergraduate teaching. The Priestley Prize is awarded annually to recognize a professor who increased learning and enthusiasm of students in chemistry courses. More information can be found here.
February 24th, 2017 Welcome Lan Pham to the O’Brien Lab. Lan is getting his Ph.D. in theoretical physics in Vietnam, and is a visiting scientist in the O’Brien Lab for the next six weeks.
February 11th, 2017 Grad student Dan Nissley attends 61st meeting of the Biophysical Society to present a talk titled “Accurate prediction of cellular co-translational folding indicates proteins can switch from post- to co-translational folding.”
November 14th, 2016 The O’Brien Lab welcomes new graduate student Joe Persichetti. Joe completed his undergraduate studies in Chemistry at Wagner College in Spring 2016.
November 7th, 2016 The O’Brien Lab welcomes new graduate student Dave Wolfe. Dave completed his undergraduate studies in Mathematics and Chemistry at St. Francis University in Spring 2016.
October 1st, 2016 The O’Brien Lab was just awarded additional funds from the National Science Foundation and the Deutsche Forschungsgemeinschaft (Germany) to support personnel exchanges between the lab and Prof. Bernd Bukau’s lab in Heidelberg, Germany, in furtherance of collaborative research efforts.
September 7th, 2016 The O’Brien Lab congratulates graduate student Dan Nissley, who received the Eberly College of Science Troxell Memorial Scholarship in recognition of his research accomplishments.
July 1st, 2016 Welcome to Dave Wolfe and Joe Persichetti, who are doing summer rotations in the O’Brien Lab.
June 14, 2016 O’Brien Lab members Ben Fritch, Vivek Gohil, and Ed O’Brien began participating in the Upward Bound Math and Science program through Penn State. They are working with four High School students on various molecular dynamic simulations that teach the principles of biophysics. These demonstrations will eventually be integrated into a portable haptic feedback arcade-style device for future outreach activities.
May 23rd, 2016 Congratulations to Fabio Trovato and Ed O’Brien on the publication of their review article “Insights into co-translational nascent protein behavior from computer simulations” in Annual Review of Biophysics
May 10, 2016 Ed O’Brien gives a talk in London at Queen Mary’s College.
February 29rd, 2016 Ed O’Brien gives a talk at the Biophysical Society National Meeting in Los Angeles.
February 27rd, 2016 The Biopolymer’s In Vivo Subgroup meeting “Translation Dynamics and Nascent Proteome Behavior” was a success. Ed O’Brien and Christian Kaiser served as program chairs and Martin Gruebele was chair.
February 23rd, 2016 Congratulations to Ben Fritch, who presented his second year seminar “Investigation of Protein Folding and Unfolding Using Optical Tweezers.”
February 9th, 2016 Congratulations to Sarah Leininger, who presented her second year seminar “Misfolding and Aggregation of the Prion Protein.”
December 30th, 2015 Congratulations to O’Brien Lab members Dr. Ajeet Sharma and Asst. Prof. Ed O’Brien for the publication of their paper “Physical Origins of Codon Positions That Strongly Influence Cotranslational Folding: A Framework for Controlling Nascent-Protein Folding” in the Journal of the American Chemical Society. Congratulations are also offered to collaborator Bernd Bukau. More details can be found here.
December 3rd, 2015 The O’Brien Lab was just awarded a National Science Foundation CAREER grant to study the origins and consequences of variable codon translation for nascent protein behavior. This five year grant will support graduate students and postdocs in the lab, as well as outreach activities to expose underrepresented groups to cutting-edge techniques and principles in theoretical and computational biophysics. More details can be found here.
December 1st, 2015 Congratulations to O’Brien group members Dan Nissley, Ajeet Sharma, Nabeel Ahmed, and Ed O’Brien for the acceptance of their manuscript “Accurate prediction of cellular co-translational folding indicates proteins can switch from post- to co-translational folding”. Additional thanks to co-authors and collaborators Ulrike Friedrich, Guenter Kramer, and Bernd Bukau of the University of Heidelberg and The German Cancer Research Center.
October 14th, 2015 Ed O’Brien gives a talk at the CECAM conference on Computational Modeling of Gene Expression and its Evolution in Tel Aviv, Israel.
October 10th, 2015 Ed O’Brien gives a talk at the NESS Symposium held at the University of Connecticut.
October 2nd, 2015 Congratulations to Nabeel Ahmed on passing his Phd comprehensive exam in the Department of Bioinformatics and Genomics!
August 1st, 2015 Ed O’Brien gives a talk at the Institute for Computational Science and Technology in Saigon, Vietnam.
July 29th, 2015 Ed O’Brien gives a talk at the International Workshop on Theoretical and Computational Physics in Da Lat, Vietnam.
July 1st, 2015 We welcome Krystal Diaz and Jeff Bacca to the O’Brien Lab as Ph.D. rotation students.
July 1st, 2015 Congratulations to Dan Nissley on passing his second year comprehensive exam in the Chemistry Department!
April 13th, 2015 Congratulations to Vivek Gohil on being awarded an Erickson Discovery Grant, which will allow Vivek to carry out research in the O’Brien Lab over the summer.
April 6th, 2015 The O’Brien Lab has been awarded a 3 year grant by the Human Frontiers Science Program to advance a quantitative, predictive understanding of translation kinetics on nascent proteome behavior. Out of approximately 1,100 letters of intent only 21 grants were awarded. This grant supports a collaborative effort between the lab and Prof. Bernd Bukau’s Lab at University of Heidelberg in Germany. More information can be found here.
February 25, 2015 Ed O’Brien is elected as a program chair for the Biopolymers In Vivo subgroup at the 2016 Biophysical Society meeting
January 26, 2015 Welcome Lok-Ken Chan to the O’Brien Lab. Lok-Ken is joining us as an undergraduate majoring in Biomedical Engineering and Physics here at Penn State.
January 09, 2015 Welcome Vivek Gohil to the O’Brien Lab. Vivek is joining us as an undergraduate majoring in Physics here at Penn State.
November 25, 2014 Congratulations to Dan Nissley on having a Perspective article published by the Journal of the American Chemical Society.
November 5, 2014 Welcome to Ben Fritch, Sarah Leininger and Nabeel Ahmed to the O’Brien Lab. Ben and Sarah are joining from the Chemistry Ph.D. Program; Nabeel from the Bioinformatics and Genomics Program.
August 20, 2014 Ed O’Brien runs the CECAM Conference he organized on “Modeling Cellular Life: From single molecules to cellular function.” More information is available here.
June 2014 Ed discusses his research with the ACS’s “Chemistry over Coffee” video series.
April 2014 Welcome to Postdocs Ajeet Sharma and Fabio Trovato to the O’Brien Lab. Ajeet is joining us after getting a Ph.D. in Physics from IIT Kanpur and Fabio is joining us after getting a Ph.D. in Physics from University of Pisa.
September 20, 2013 Welcome Dan Nissley, who has joined the O’Brien Lab as part of the Chemistry Ph.D. Program.